Genomics England
GMS Panels
Panels
Genes and Entities

APP

amyloid beta precursor protein
OMIM: 104760
PanelMode of inheritanceDetails
2 panels
Green
in Leukodystrophy, adult onset
R-numbers: R62
Signed-off version 7.8
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Cerebral amyloid angiopathy, Dutch, Italian, Iowa, Flemish, Arctic variants, OMIM:605714
Green
in Neurodegenerative disorders, adult onset
Component of the following Super Panels:
  • - Adult-onset neurological disorders
Signed-off version 9.4
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Alzheimer disease 1, familial, OMIM:104300, Cerebral amyloid angiopathy, Dutch, Italian, Iowa, Flemish, Arctic variants, OMIM:605714