Genomics England
GMS Panels
Panels
Genes and Entities

CDKN2A

cyclin dependent kinase inhibitor 2A
OMIM: 600160
PanelMode of inheritanceDetails
4 panels
Green
in Adult solid tumours cancer susceptibility
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Familial Malignant Melanoma and Tumors of the Nervous system, Familial Uveal Melanoma
Green
in Familial melanoma
R-numbers: R254
Signed-off version 2.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
{Melanoma, cutaneous malignant, 2}, OMIM:155601, {Melanoma and neural system tumor syndrome}, OMIM:155755, {Melanoma-pancreatic cancer syndrome}, OMIM:606719
Green
in Inherited pancreatic cancer
R-numbers: R367
Signed-off version 2.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
{Melanoma-pancreatic cancer syndrome}, OMIM:606719, Melanoma-pancreatic cancer syndrome, MONDO:0011713
Green
in Pigmentary skin disorders
R-numbers: R236
Signed-off version 3.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
{Melanoma, cutaneous malignant, 2}, OMIM:155601, {Melanoma and neural system tumor syndrome}, OMIM:155755, {Melanoma-pancreatic cancer syndrome}, OMIM:606719