Genomics England
GMS Panels
Panels
Genes and Entities

DDX41

DEAD-box helicase 41
OMIM: 608170
PanelMode of inheritanceDetails
3 panels
Green
in Cytopenia - NOT Fanconi anaemia
R-numbers: R91
Signed-off version 3.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to, 616871
Green
in Haematological malignancies cancer susceptibility
Signed-off version 4.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Class: familial predisp to leukaemia (typ AD), DDX41-related AML, SCN3, AML, MDS (late onset), possibly others, CML, No other known cancer risks
Green
in Inherited predisposition to acute myeloid leukaemia (AML)
R-numbers: R347
Signed-off version 3.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
{Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to}, OMIM:616871, DDX41-related hematologic malignancy predisposition syndrome, MONDO:0014809