Genomics England
GMS Panels
Panels
Genes and Entities

FASLG

Fas ligand
OMIM: 134638
PanelMode of inheritanceDetails
2 panels
Green
in Cytopenia - NOT Fanconi anaemia
R-numbers: R91
Signed-off version 5.0
BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Autoimmune lymphoproliferative syndrome, type IB, OMIM:601859
Green
in Primary immunodeficiency or monogenic inflammatory bowel disease
R-numbers: R15
Signed-off version 9.0
BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Autoimmune lymphoproliferative syndrome, type IB, OMIM:601859, autoimmune lymphoproliferative syndrome type 1, MONDO:0011158, systemic lupus erythematosus (SLE)