Genomics England
GMS Panels
Panels
Genes and Entities

GLIS3

GLIS family zinc finger 3
OMIM: 610192
PanelMode of inheritanceDetails
5 panels
Green
in Congenital hypothyroidism
R-numbers: R145
Signed-off version 2.2
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Congenital hypothyroidism, Diabetes mellitus, neonatal, with congenital hypothyroidism, 610199, neonatal non-autoimmune diabetes mellitus, severe congenital hypothyroidism, variable cholestasis, hepatic fibrosis, congenital glaucoma, polycystic kidneys, dysmorphic facies, sensorineural deafness
Green
in DDG2P
Component of the following Super Panels:
  • - Paediatric disorders
Signed-off version 5.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
DIABETES MELLITUS NEONATAL WITH CONGENITAL HYPOTHYROIDISM 610199
Green
in Fetal anomalies
R-numbers: R21, R412
Signed-off version 5.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
DIABETES MELLITUS NEONATAL WITH CONGENITAL HYPOTHYROIDISM
Green
in Intellectual disability
Component of the following Super Panels:
  • - Childhood onset leukodystrophy
  • - Hypotonic infant
  • - Paediatric disorders
R-numbers: R29
Signed-off version 8.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Diabetes mellitus, neonatal, with congenital hypothyroidism, 610199
Green
in Neonatal diabetes
R-numbers: R143
Signed-off version 5.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Diabetes mellitus, neonatal, with congenital hypothyroidism, OMIM:610199