Genomics England
GMS Panels
Panels
Genes and Entities

NF2

neurofibromin 2
OMIM: 607379
PanelMode of inheritanceDetails
6 panels
Green
in Adult solid tumours cancer susceptibility
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Acoustic neuroma
Green
in Bilateral congenital or childhood onset cataracts
R-numbers: R31
Signed-off version 6.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Green
in Childhood solid tumours
R-numbers: R359
Signed-off version 4.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Meningioma, NF2-related, somatic, 607174, Schwannomatosis, 162091, Neurofibromatosis, Type 2, Neurofibromatosis, Type II, loss of heterozygosity Neurofibromatosis, type 2, 101000, Acoustic neuroma
Green
in Familial tumours of the nervous system
R-numbers: R221
Signed-off version 2.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Green
in Mosaic skin disorders - deep sequencing
R-numbers: R327
Signed-off version 2.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
NEUROFIBROMATOSIS, TYPE II, NF2
Green
in Pigmentary skin disorders
R-numbers: R236
Signed-off version 3.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
NF2, Neurofibromatosis type 2, NEUROFIBROMATOSIS, TYPE II