Genomics England
GMS Panels
Panels
Genes and Entities

TBK1

TANK binding kinase 1
OMIM: 604834
PanelMode of inheritanceDetails
3 panels
Green
in Adult onset dystonia, chorea or related movement disorder
R-numbers: R56
Signed-off version 4.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Frontotemporal dementia and/or amyotrophic lateral sclerosis 4, OMIM:616439
Green
in Adult onset neurodegenerative disorder
R-numbers: R58
Signed-off version 7.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Frontotemporal dementia and/or amyotrophic lateral sclerosis 4, OMIM:616439
Green
in Primary immunodeficiency or monogenic inflammatory bowel disease
R-numbers: R15
Signed-off version 7.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Herpes simplex encephalitis, susceptibility to, Herpetic encephalitis (HSE), {Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 8} 617900, Herpes simplex virus 1 encephalitis, Defects in Intrinsic and Innate Immunity