Genomics England
GMS Panels
Panels
Genes and Entities

TFG

TRK-fused gene
OMIM: 602498
PanelMode of inheritanceDetails
4 panels
Green
in Hereditary neuropathy or pain disorder
R-numbers: R78
Signed-off version 8.30
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
Hereditary motor and sensory neuropathy, Okinawa type, OMIM:604484, Spastic paraplegia 57, autosomal recessive, OMIM:615658
Green
in Hereditary spastic paraplegia, childhood onset
R-numbers: R61
Signed-off version 9.7
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Spastic paraplegia 57, autosomal recessive, OMIM:615658
Green
in Intellectual disability
Component of the following Super Panels:
  • - Hypotonic infant
  • - Leukodystrophy, childhood onset
  • - Paediatric disorders
Signed-off version 11.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Spastic paraplegia 57, autosomal recessive, OMIM:615658
Green
in Optic neuropathy
R-numbers: R41
Signed-off version 6.46
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Spastic paraplegia 57, autosomal recessive, OMIM:615658