Genomics England

TRK-fused gene

Panel	Mode of inheritance	Details
Filter panels4 panels
Green in Childhood onset hereditary spastic paraplegia R-numbers: R61 Signed-off version 9.0	BIALLELIC, autosomal or pseudoautosomal	Phenotypes Spastic paraplegia 57, autosomal recessive, OMIM:615658
Green in Hereditary neuropathy or pain disorder R-numbers: R78 Signed-off version 8.0	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Hereditary motor and sensory neuropathy, Okinawa type, OMIM:604484, Spastic paraplegia 57, autosomal recessive, OMIM:615658
Green in Intellectual disability Component of the following Super Panels: - Childhood onset leukodystrophy - Hypotonic infant - Paediatric disorders R-numbers: R29 Signed-off version 10.0	BIALLELIC, autosomal or pseudoautosomal	Phenotypes Spastic paraplegia 57, autosomal recessive, OMIM:615658
Green in Optic neuropathy R-numbers: R41 Signed-off version 6.0	BIALLELIC, autosomal or pseudoautosomal	Phenotypes Spastic paraplegia 57, autosomal recessive, OMIM:615658