Genomics England
GMS Panels
Panels
Genes and Entities

XK

X-linked Kx blood group
OMIM: 314850
PanelMode of inheritanceDetails
4 panels
Green
in Adult onset dystonia, chorea or related movement disorder
Component of the following Super Panels:
  • - Adult-onset neurological disorders
Signed-off version 6.0
X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
Phenotypes
McLeod syndrome, OMIM:300842
Green
in Adult onset neurodegenerative disorder
Component of the following Super Panels:
  • - Adult-onset neurological disorders
R-numbers: R58
Signed-off version 9.0
X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
Phenotypes
McLeod syndrome with or without chronic granulomatous disease, OMIM:300842, McLeod neuroacanthocytosis syndrome, MONDO:0018945
Green
in Hereditary neuropathy or pain disorder
R-numbers: R78
Signed-off version 8.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
Mceod syndrome, Onset 25-60, acanthocytes and Huntington-like syndrome, also epilepsy, cardiomyopathy, axonal motor neuropathy, McLeod syndrome with or without chronic granulomatous disease, 300842
Green
in Rare anaemia
R-numbers: R92
Signed-off version 4.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
McLeod syndrome with or without chronic granulomatous disease, OMIM:300842, McLeod neuroacanthocytosis syndrome, MONDO:0018945