Genomics England

This cancer panel will be applied as appropriate in the GMS cancer pipeline and is not requestable separately.

Relevant disorders: Ovarian

Signed off date: 22 Mar 2023

Panel types: Cancer Germline 100K, GMS Cancer Germline Virtual, GMS signed-off

8 green entities

Entity rating	Entity	Mode of inheritance	Mode of pathogenicity	Tags
Green	BRCA1	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	N/A	N/A
Green	BRCA2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	BRIP1	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A
Green	MLH1	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MSH2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MSH6	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	RAD51C	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	RAD51D	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A