Genomics England
GMS Panels
Panels
Genes and Entities

FLCN

folliculin
OMIM: 607273
PanelMode of inheritanceDetails
6 panels
Green
in Adult solid tumours cancer susceptibility
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
renal oncocytoma
Green
in Cystic kidney disease
Component of the following Super Panels:
  • - Cystic renal disease
Signed-off version 6.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Birt-Hogg-Dube syndrome, OMIM:135150, renal cysts, cutaneous fibrofolliculoma, pneumothorax, pulmonary cysts, renal cell carcinoma, renal oncocytoma
Green
in Inherited renal cancer
R-numbers: R224
Signed-off version 1.2
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Renal carcinoma, Parotid oncocytomas, Neural tissue tumors, Lipomas, Angiolipomas
Green
in Multiple monogenic benign skin tumours
R-numbers: R230
Signed-off version 2.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Birt-Hogg-Dub syndrome, OMIM:135150
Green
in Pneumothorax - familial
R-numbers: R190
Signed-off version 3.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Pneumothorax, primary spontaneous, OMIM:173600, Birt-Hogg-Dube Syndrome, OMIM:135150
Green
in Unexplained young onset end-stage renal disease
R-numbers: R257
Signed-off version 5.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Birt-Hogg-Dube syndrome, OMIM:135150, renal cell carcinoma, renal cysts, pneumothorax, renal oncocytoma, pulmonary cysts, cutaneous fibrofolliculoma