Genomics England
GMS Panels
Panels
Genes and Entities

IDS

iduronate 2-sulfatase
OMIM: 300823
PanelMode of inheritanceDetails
9 panels
Green
in DDG2P
Component of the following Super Panels:
  • - Paediatric disorders
Signed-off version 5.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
MUCOPOLYSACCHARIDOSIS TYPE 2 309900
Green
in Fetal anomalies
R-numbers: R21, R412
Signed-off version 5.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
MUCOPOLYSACCHARIDOSIS TYPE 2
Green
in Hydrocephalus
R-numbers: R86
Signed-off version 5.0
X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
Phenotypes
Mucopolysaccharidosis II, OMIM:309900
Green
in Intellectual disability
Component of the following Super Panels:
  • - Childhood onset leukodystrophy
  • - Hypotonic infant
  • - Paediatric disorders
R-numbers: R29
Signed-off version 8.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
Mucopolysaccharidosis II, 309900, MUCOPOLYSACCHARIDOSIS TYPE 2 (MPS2)
Green
in Likely inborn error of metabolism
Component of the following Super Panels:
  • - Childhood onset leukodystrophy
  • - Hypotonic infant
  • - Paediatric disorders
  • - Unexplained death in infancy and sudden unexplained death in childhood
R-numbers: R98
Signed-off version 7.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
MUCOPOLYSACCHARIDOSIS TYPE 2, MPS II, Hunter disease (Mucopolysaccharidoses), Mucopolysaccharidosis II, 309900, Mucopolysaccharidosis Type II
Green
in Lysosomal storage disorder
R-numbers: R276
Signed-off version 3.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
Mucopolysaccharidosis II OMIM:309900, mucopolysaccharidosis type 2 MONDO:0010674
Green
in Mucopolysaccharidosis type II
R-numbers: R278
Signed-off version 1.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
Green
in Rare syndromic craniosynostosis or isolated multisuture synostosis
R-numbers: R100
Signed-off version 5.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
Mucopolysaccharidosis II (MPS2, Hunter syndrome) 309900, 309900
Green
in Skeletal dysplasia
Component of the following Super Panels:
  • - Paediatric disorders
R-numbers: R104
Signed-off version 7.0
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Phenotypes
Mucopolysaccharidosis II 309900