KRAS

KRAS proto-oncogene, GTPase
OMIM: 190070
PanelMode of inheritanceDetails
12 panels
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Noonan syndrome 3 609942, Cardiofaciocutaneous syndrome 2 615278
R-numbers: R135
Signed-off version 1.4
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Noonan syndrome 3, Noonan syndrome, CFC syndrome, Cardiofaciocutaneous syndrome 2 615278, Noonan syndrome 3 609942, Cardiofaciocutaneous syndrome 2, Cardiofaciocutaneous Syndrome, Cardio-Facio-Cutaneous syndrome
R-numbers: R100
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
cardiofaciocutaneous syndrome type 2 615278, Noonan syndrome type 3 609942, 615278, 609942
Green
in DDG2P
Component of the following Super Panels:
  • - Paediatric disorders
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
CARDIOFACIOCUTANEOUS SYNDROME 115150, NOONAN SYNDROME TYPE 3 609942
R-numbers: R21
Signed-off version 1.92
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
NOONAN SYNDROME TYPE 3, CARDIOFACIOCUTANEOUS SYNDROME
R-numbers: R59
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Cardiofaciocutaneous syndrome 2, 615278
R-numbers: R147
Signed-off version 1.4
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Rasopathy, Noonan syndrome, CFC syndrome, Cardiofaciocutaneous syndrome 2, Noonan syndrome 3, Cardiofaciocutaneous Syndrome, Cardio-Facio-Cutaneous syndrome
Component of the following Super Panels:
  • - Hypotonic infant
  • - Paediatric disorders
  • - White matter disorders - childhood onset
R-numbers: R29
Signed-off version 3.2
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Lung cancer, somatic, 211980Bladder cancer, somatic, 109800Pancreatic carcinoma, somatic, 260350Gastric cancer, somatic, 137215Leukemia, acute myelogenousNoonan syndrome 3, 609942Cardiofaciocutaneous syndrome 2, 615278Breast cancer, somatic, 114480SFM syndrome, somatic mosaic, 163200, CARDIOFACIOCUTANEOUS SYNDROME (CFC SYNDROME)
R-numbers: R327
Signed-off version 1.3
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Schimmelpenning syndrome, Epidermal naevi
R-numbers: R236
Signed-off version 1.4
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
NOONAN SYNDROME 3, CARDIOFACIOCUTANEOUS SYNDROME 2, NOONAN SYNDROME 3, 609942, CFC2
R-numbers: R136
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Noonan syndrome 3 609942, Cardiofaciocutaneous syndrome 2 615278
R-numbers: R359
Signed-off version 2.5
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Noonan syndrome 3 609942, Cardiofaciocutaneous syndrome 2 615278