Genomics England

LZTR1

leucine zipper like transcription regulator 1

Panel	Mode of inheritance	Details
Filter panels6 panels
Green in Fetal anomalies R-numbers: R21, R412 Signed-off version 3.0	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Fetal hydrops, Noonan syndrome 10, 616564
Green in Growth failure in early childhood R-numbers: R147 Signed-off version 3.0	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Noonan syndrome 10, increased nuchal translucency, Prenatal hydrops, cardiac findings
Green in Intellectual disability - microarray and sequencing Component of the following Super Panels: - Childhood onset leukodystrophy - Hypotonic infant - Paediatric disorders R-numbers: R29 Signed-off version 5.0	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Noonan syndrome 10, Prenatal hydrops, increased nuchal translucency, cardiac findings
Green in Paediatric or syndromic cardiomyopathy Component of the following Super Panels: - Unexplained death in infancy and sudden unexplained death in childhood R-numbers: R135 Signed-off version 3.0	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Schwannomatosis-2, susceptibility to 615670, Noonan syndrome 10 616564
Green in Pigmentary skin disorders R-numbers: R236 Signed-off version 3.0	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes NOONAN SYNDROME 10, NS2, NS10, NOONAN SYNDROME 2, Schwannomatosis-2, susceptibility to 615670, Noonan syndrome 10 616564
Green in Primary lymphoedema R-numbers: R136 Signed-off version 3.0	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Schwannomatosis-2, susceptibility to 615670, Noonan syndrome 10 616564