Genomics England
GMS Panels
Panels
Genes and Entities

STRADA

STE20-related kinase adaptor alpha
OMIM: 608626
PanelMode of inheritanceDetails
6 panels
Green
in DDG2P
Component of the following Super Panels:
  • - Paediatric disorders
Signed-off version 6.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Polyhydramnios, megalencephaly, and symptomatic epilepsy, OMIM:611087
Green
in Early onset or syndromic epilepsy
Component of the following Super Panels:
  • - Paediatric disorders
  • - Unexplained death in infancy and sudden unexplained death in childhood
R-numbers: R59
Signed-off version 8.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Polyhydramnios, megalencephaly, and symptomatic epilepsy 611087
Green
in Fetal anomalies
R-numbers: R21, R412
Signed-off version 6.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Polyhydramnios, megalencephaly, and symptomatic epilepsy, OMIM:611087, Polyhydramnios, megalencephaly, and symptomatic epilepsy, MONDO:0012611
Green
in Hydrocephalus
R-numbers: R86
Signed-off version 5.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Polyhydramnios, megalencephaly, and symptomatic epilepsy, OMIM:611087
Green
in Intellectual disability
Component of the following Super Panels:
  • - Childhood onset leukodystrophy
  • - Hypotonic infant
  • - Paediatric disorders
R-numbers: R29
Signed-off version 9.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Polyhydramnios, megalencephaly, and symptomatic epilepsy, MIM:611087 (includes mental retardation), severe psychomotor retardation
Green
in Nephrocalcinosis or nephrolithiasis
Component of the following Super Panels:
  • - Unexplained young onset end-stage renal disease
R-numbers: R256
Signed-off version 5.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Polyhydramnios, megalencephaly, and symptomatic epilepsy, 611087