Genomics England

Genes and Entities

Inherited prostate cancer (Version: )

Relevant disorders: R430

Signed off date: 6 May 2026

Panel types: GMS Rare Disease Virtual, GMS Rare Disease, GMS signed-off

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8 green entities

Entity rating	Entity	Mode of inheritance	Mode of pathogenicity	Tags
Green	ATM	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	BRCA1	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	BRCA2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	CHEK2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MLH1	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MSH2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MSH6	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	PALB2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A