Genomics England

This cancer panel will be applied as appropriate in the GMS cancer pipeline and is not requestable separately.

There is a more recent signed-off version of this panel

Relevant disorders: Breast

Signed off date: 29 Sept 2021

Panel types: Cancer Germline 100K, GMS Cancer Germline Virtual, GMS signed-off

4 green entities

Entity rating	Entity	Mode of inheritance	Mode of pathogenicity	Tags
Green	BRCA1	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	BRCA2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	PALB2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	TP53	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A