Genomics England

Genes and Entities

Inherited breast cancer and ovarian cancer (Version: )

Relevant disorders: R208

Signed off date: 12 Apr 2023

Panel types: GMS Rare Disease, GMS signed-off

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7 green entities

Entity rating	Entity	Mode of inheritance	Mode of pathogenicity	Tags
Green	ATM	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	BRCA1	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	N/A	N/A
Green	BRCA2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	CHEK2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	PALB2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	RAD51C	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A
Green	RAD51D	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A