Genomics England

Genes and Entities

Inherited predisposition to acute myeloid leukaemia (AML) (Version: )

Relevant disorders: R347

Signed off date: 22 Mar 2023

Panel types: GMS Rare Disease, GMS signed-off

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11 green entities

Entity rating	Entity	Mode of inheritance	Mode of pathogenicity	Tags
Green	ANKRD26	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	CEBPA	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	DDX41	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	ETV6	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	GATA2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MBD4	BIALLELIC, autosomal or pseudoautosomal	N/A	N/A
Green	RUNX1	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	SAMD9L	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A
Green	TERC	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	TERT	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	N/A	N/A
Green	TP53	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A